Cancer Science & Therapy

Mayer J

Publications

• Research Article
  Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer
  Author(s): Brancíková D, Mechl Z, Adam Z, Protivánková M, Ostrížková L, Bednarík O and Mayer JBrancíková D, Mechl Z, Adam Z, Protivánková M, Ostrížková L, Bednarík O and Mayer J
  
  Bone metastases and treatment-induced osteoporosis are frequently the maincauses of morbidity in patients with malignancies. Monitoring the level of bone markers (markers of bone metabolism) has been fairly well mapped in osteoporosis, where medical procedures can be modified according to the kinetics of marker levels before an answer can be evaluated by densitometry and before the onset of fractures. In bone metastases the role of these levels is not clear. The metabolic markers of bone resorption under review in this set were ß-Cross Laps (CTX) - a peptide that is a part of C - telopeptide, and N-terminal propeptide of collagen type 1 (P1NP). Material and methods: We monitored a group of 52 female patients with metastatic breastcancer. The patients received appropriate systemic treatment based o.. Read More»
  DOI: 10.4172/1948-5956.1000244

  Abstract PDF