Journal of Bioanalysis & Biomedicine

Md. Didaruzzaman Sohel

Publications

• Research Article
  In Vitro Dissolution Study and Assay of Diclofenac Sodium from Marketed Solid Dosage form in Bangladesh
  Author(s): Tania Sultana, Md. Didaruzzaman Sohel, Md. Hassan Kawsar and Rebecca BanooTania Sultana, Md. Didaruzzaman Sohel, Md. Hassan Kawsar and Rebecca Banoo
  
  The aim of this study is to determine the potency of drug available in our market in Bangladesh. Diclofenac Sodium is a potent Non-Steroidal Anti-Inflammatory Drug (NSAID) and that are widely used and it is an Over the Counter (OTC) drug in Bangladesh. Potency determination was performed to evaluate that the marketed sample comply with the declared specification or not. In vitro Dissolution study was performed to see that if potency is high but the drug is not bioavailable. Hardness is also checked to see that whether it interfere with the dissolution which ultimately effect the bioavailability. In this present study a simple, cost effective and spectrophotometric method for the potency determination of marketed Diclofenac Sodium tablets is used. Four samples were randomly collected from the market and coded as D01, D02, D03 and D04 and the potency determined are 99.30%, 103.38%, 98.2.. Read More»
  DOI: 10.4172/1948-593X.1000164

  Abstract PDF