Journal of Clinical Case Reports

Megan Toufexis

Publications

• Case Report
  A Possible Link Between Tic Disorders Associated with Beta Thalassemia Minor and Sickle Cell Disease
  Author(s): Megan Toufexis, Adam B. Lewin, Eric A Storch, Caroline DeOleo and Tanya K MurphyMegan Toufexis, Adam B. Lewin, Eric A Storch, Caroline DeOleo and Tanya K Murphy
  
  Background: Genetic linkages with psychiatric disorders have been documented. In our clinical practice, we noticed a high propensity for blood disorders in female patients with certain neuropsychiatric phenomenon, specifically Tourette Syndrome (TS) or Trichotillomania (TTM). With this clinical observation, we hoped to better understand a possible genetic correlation, namely the role of chromosome 11 which encodes for both the B globulin gene and human dopamine receptor D4 (DRD4) gene. Method: This is a retrospective case series of six children found to have a blood disorder and neuropsychiatric diagnosis in our clinic. We used family interview, lab results, and the patient’s medical chart for data collection Results: Our case series reveals six children with a repetitive neuropsychiatric disorder and a blood disorder. Conclusions: Currently, there are no definitive susceptibili.. Read More»
  DOI: 10.4172/2165-7920.1000244

  Abstract PDF