Journal of Cytology & Histology

Megha

Publications

• Research Article
  Morphometric Analysis and Immunocytochemical Staining on Cytospin Preparation in Effusion Cytology: A Study
  Author(s): Rajeev Sen, Sonia Hasija, Rajnish Kalra, Shilpa Garg, Ajeet Singh and MeghaRajeev Sen, Sonia Hasija, Rajnish Kalra, Shilpa Garg, Ajeet Singh and Megha
  
  Introduction: Morphological differentiation between reactive mesothelial proliferation and metastatic carcinoma cells may be extremely difficult in conventional centrifuge deposit smears stained with papanicolaou and romanowsky dyes. In the present study immunocytochemistry and morphometric analysis were performed on cytospin preparation of effusion categorized as atypical/suspicious on toluidine blue stained wet films. Materials and methods: A total of 100 cases comprising 26 benign (control group) and 74 malignant (study group) effusions were included in the study. Samples showing atypical /suspicious cells on preliminary conventional centrifuged wet film stained with toluidine blue; 63 were aspirated from pleural, 36 from peritoneal and 1 from pericardial effusions. These samples were processed for 6 cytospin preparations, 1 air dried stain.. Read More»
  DOI: 10.4172/2157-7099.1000314

  Abstract PDF