Journal of Hypertension: Open Access

Menghui Wang

Publications

• Research Article
  Case Detection Testing for Primary Aldosteronism in Male Patients with Hypertension and Snoring
  Author(s): Menghui Wang, Nanfang Li, Ying Zhang, Delian Zhang, Suofeiya Abulikemu, Yinchun Wang, Guli Nuer, Jianqiong Kong, Juhong Zhang, Zhitao Yan, Hongjian Li and Xiangyang ZhangMenghui Wang, Nanfang Li, Ying Zhang, Delian Zhang, Suofeiya Abulikemu, Yinchun Wang, Guli Nuer, Jianqiong Kong, Juhong Zhang, Zhitao Yan, Hongjian Li and Xiangyang Zhang
  
  Objectives: Coexistence of primary aldosteronism and obstructive sleep apnea in hypertension is evidenced. However, aldosterone and renin activity is varying with apnea/hypopnea index changes in subjects with resistant hypertension. Thus, the aim is to investigate the optional cutoff value for aldosterone/renin activity to screen primary aldosteronism in patients with different status of apnea/hypopnea index. Methods: 271 hypertensive male snores were evaluated via polysomnography and divided into two groups, group with apnea/hypopnea index >15 events/h and with apnea/hypopnea index <15 events/h. Primary aldosteronism was determined as following: subjects with plasma renin activity<1.0 ng/mL/h and aldosterone concentration>15 ng/dL performed saline infusion test, after which aldosterone concentration>5 ng/dL was a sign of prim.. Read More»
  DOI: 10.4172/2167-1095.1000180

  Abstract PDF