Molecular Biomarkers & Diagnosis

Mervat Soltan

Publications

• Research Article
  Hepatic Progenitor Cells and Cells Resistant to Apoptosis in Chronic HCV
  Author(s): Maha M El-Sabaawy, Eman Abdelsameea, Ayat R Abdallah, Ahmed El-Refaey, Mervat Soltan and Nemine EhsanMaha M El-Sabaawy, Eman Abdelsameea, Ayat R Abdallah, Ahmed El-Refaey, Mervat Soltan and Nemine Ehsan
  
  Background: Hepatic progenitor cells (HPC) as a hepatic regeneration reservoir, are now signified as one of the promising therapeutics. However, connection to cells resistant to apoptosis in pathogenesis of chronic hepatitis C virus (HCV) is still evolving. Aim: title relationship between HPC and cells resistant to apoptosis in HCV along with liver disease severity and fibrosis progression. Methods: liver biopsies of 91 chronic HCV patients were immunohistochemically examined. Both demographic and clinical characteristics were sourced from the data registries. METAVIR scoring was unified for both Grading and staging. Immunostaining with CK7, Ki67, and bcl2 antibodies was done. Results: Transaminases, platelets and prothrombin time exhibited significant relation with Ki67, CK7 both isolated and ductular and bcl2 bot.. Read More»
  DOI: 10.4172/2155-9929.1000352

  Abstract PDF