Journal of Tissue Science and Engineering

Meyer Christof

Publications

• Research Article
  (Ultra) Structural Details of Cells and Matrix during Early Cartilage Regeneration after Chondrocyte Implantation in the Equine Knee Joint
  Author(s): Nurnberger Sylvia, Barnewitz Dirk Dvm, Tichy Brigitte, Ponomarev Igor, Meyer Christof, Klepal W, Albrecht Christian and Marlovits StefanNurnberger Sylvia, Barnewitz Dirk Dvm, Tichy Brigitte, Ponomarev Igor, Meyer Christof, Klepal W, Albrecht Christian and Marlovits Stefan
  
  Objective: This pilot study of cartilage defect treatment was designed to establish the horse as a suitable animal model for MACT (Matrix-Associated Autologous Chrondrocyte Transplantation) transplants and to analyse the morphological aspects of repair tissue development and differentiation. Design: Hyaluronan-based and collagen-based biodegradable scaffolds were seeded with autologous chondrocytes and implanted into large (1.5×2 cm) defects in the trochlear ridge of the distal femur of three horses. A non-treated, empty defect was used as control. Three months after surgery, samples of the defect area were investigated using bright field and polarized light microscopy, immunohistochemistry and electron microscopy. Results: In MACT-treated lesions with good defect filling, the repair tissue integrated well into the defect and showed features of differentiation in transition to n.. Read More»
  DOI: 10.4172/2157-7552.S2-004

  Abstract PDF