Journal of Hypertension: Open Access

Michael A Joseph

Publications

• Research Article
  Impact of Kidney Function on Effects of the Dietary Approaches to Stop Hypertension (Dash) Diet
  Author(s): Crystal C Tyson, Maragatha Kuchibhatla, Uptal D Patel, Patrick H Pun, Alex Chang, Chinazo Nwankwo, Michael A Joseph and Laura P SvetkeyCrystal C Tyson, Maragatha Kuchibhatla, Uptal D Patel, Patrick H Pun, Alex Chang, Chinazo Nwankwo, Michael A Joseph and Laura P Svetkey
  
  Objectives: Although the Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure in adults with hypertension, how kidney function impacts this effect is not known. We evaluated whether Estimated Glomerular Filtration Rate (eGFR) modifies the effect of the DASH diet on blood pressure, markers of mineral metabolism, and markers of kidney function. Methods: Secondary analysis of the DASH-Sodium trial, a multicenter, randomized, controlled human feeding study that evaluated the blood pressure lowering effect of the DASH diet at three levels of sodium intake. Data from 92 participants with pre-hypertension or stage 1 hypertension during the 3450 mg /day sodium diet assignment contributed to this analysis. Stored frozen plasma and urine specimens were used to measure kidney related laboratory outcomes. Results:.. Read More»
  DOI: 10.4172/2167-1095.1000168

  Abstract PDF