Molecular Biology: Open Access

Michael RR

Publications

• Research Article
  Analysis of Synapsin I and II mRNAs and Proteins During Murine Development
  Author(s): Michael RRMichael RR
  
  The synapsins are a family of neuronal phosphoproteins that have been previously shown to play an important regulatory role in the release of neurotransmitter from the presynaptic terminal and in the process of synaptogenesis. The mechanisms that regulate the formation of synaptic terminals are a central process in determining the specificity of synaptogenesis and the development of the nervous system. Proteins involved in neurotransmitter release and the control of this release process (specifically synaptic vesicle proteins) have been implicated as being important for synaptogenesis. To determine whether synapsin is expressed at times during mouse development when synaptogenic activity is high, we examined the time course of synapsin I and II mRNA and protein expression in embryonic and postnatal mice using Northern blot and Western blot analyses. Quantification of these blot analys.. Read More»
  DOI: 10.4172/2168-9547.1000192

  Abstract PDF