Cancer Science & Therapy

Misun Hwang

Publications

• Research Article
  The Aurora Kinase A Polymorphisms are not Associated with Recurrence-free Survival in Prostate Cancer Patients
  Author(s): Jerry J. Jaboin, Natalie L. Ausborn, Misun Hwang, Heidi Chen, Kenneth J. Niermann, Nicholas J. Giacalone, Regina Courtney, Qiuyin Cai and Bo LuJerry J. Jaboin, Natalie L. Ausborn, Misun Hwang, Heidi Chen, Kenneth J. Niermann, Nicholas J. Giacalone, Regina Courtney, Qiuyin Cai and Bo Lu
  
  Background:The purpose of this study was to investigate the association between haplotype-tagging single nucleotide polymorphisms (SNPs) within the Aurora Kinase A (AURKA) gene and prostate cancer outcomes in patients with clinically localized prostate cancer. Methods:Four intronic haplotype-tagging SNPs within the AURKA gene were individually selected and examined in regard to their influence on clinical outcomes in 212 patients who underwent radical prostatectomy as first-line treatment. Haplotype-tagging SNPs were selected using the ABI SNP Browser to cover SNPs with an r2 of 0.90 or greater in the AURKA gene with a minor allele frequency of at least 0.25. Results:In our study, a log-rank univariate analysis was performed to identify significant associations between probability of recurrence-f.. Read More»
  DOI: 10.4172/1948-5956.1000105

  Abstract PDF