Japan
Research Article
Development of Label-Free Impedimetric hCG-Immunosensor Using Screen-Printed Electrode
Author(s): Truong TN Lien, Nguyen Xuan Viet, Miyuki Chikae, Yoshiaki Ukita and Yuzuru TakamuraTruong TN Lien, Nguyen Xuan Viet, Miyuki Chikae, Yoshiaki Ukita and Yuzuru Takamura
Screen-printing (thick-film) technology is well identified as a reliable technique for fabrication of electrodes which can be used as transducer in biosensor, with several advantages including low cost, design flexibility, process automation, good reproducibility and a wide choice of materials. However, the immobilization of antibody molecules is a decisive factor for successful fabrication of immunosensors. Besides, the ability to measure human Chorionic Gonadotropin (hCG) is important in establishing the diagnosis of gestational trophoblastic disease and germ cell tumors. Moreover, Electrochemical Impedance Spectroscopy (EIS) recently has been being chosen as a main detection method because it is label-free, less destructive to the activities of biomolecule and very sensitive with comparable detection limits as optical-based sensor. In this work, a sensi.. Read More»
DOI:
10.4172/2155-6210.1000107
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