Nuclear Medicine & Radiation Therapy

Moftah BA

Publications

• Research Article
  Radiotherapy Dose Escalation with Concurrent Chemotherapy Improves Outcome in Locally Advanced Cervix Carcinoma
  Author(s): Hegazy MW, Mahmood R, Albadawi I, H Husaini and Moftah BAHegazy MW, Mahmood R, Albadawi I, H Husaini and Moftah BA
  
  Background: To evaluate radiotherapy dose escalation using volumetric modulated arc therapy (VMAT) and image guided radiotherapy (IGRT) with concurrent chemotherapy in locally advanced cervix cancer (LACC) and compare it with conventional radiation therapy (CRT) in terms of the toxicity and clinical outcomes. Methods and Materials: Data base was reviewed for all LACC patients treated either by conventional radiation therapy or dose escalation volumetric modulated arc therapy, with concurrent weekly Cisplatin 40 mg/m2 followed by high dose rate brachytherapy. The primary and secondary endpoints were toxicity, disease-free survival and overall survival respectively. Results: Of 60 patients, 40 patients received CRT and 20 received VMAT. The median follow-up time in the CRT arm was 47 months (11-89), and 35 months (13-47) in the VMAT arm. Hemoglobin toxicity (Grade I-II) was encountered .. Read More»
  DOI: 10.4172/2155-9619.1000304

  Abstract PDF