Molecular Biology: Open Access

Mohadese Akhzari

Publications

• Research Article
  The Effect of Citrullus Colocynthis on the Reduction of InflammatoryAgents in Osteoarthritis
  Author(s): Mohadese Akhzari, Maryam Mirghiasi S, Mahnesa Vassaf, Maryam Sadat Mesbahi Bidgoli and Zahra Shirkhodae TariMohadese Akhzari, Maryam Mirghiasi S, Mahnesa Vassaf, Maryam Sadat Mesbahi Bidgoli and Zahra Shirkhodae Tari
  
  Nowdays, the use of medicinal plants has been very common. Colocynth, Scientific name is Citrullus colocynthis in traditional medicine used to relieve pain and inflammation. The of aim of this study is to evaluate the effects of ethanol extract of Colocynth root on pro-inflammatory cytokine COX-2, INOS, IL-1β , TNF-α and NO, PGE2 on Inflammatory cells, similar osteoarthritis in chondrocyte cells and monocytes/macrophages and then treating them. At first the ethanol extract of the Citrullus colocynthis plant was prepared from the Iranian biological resource center. Then chondrocyte cells and THP-1 monocyte / macrophages (5 × 105 cells/well) were incubated at a humidity of 90%, 5% CO2, 37ºC for 72 h with control media alone or Citrullus colocynthis at concentrations of 70 μg/ml. One set of cells was activated by 20 μl.. Read More»
  DOI: 10.4172/2168-9547.1000147

  Abstract PDF