Molecular Biology: Open Access

Mohammad Afaque Alam

Publications

• Review Article
  Is Cardiac Stem Cell Therapy a New Horizon of Heart Regeneration: Literature Review
  Author(s): Mohammad Afaque Alam, Muhammad Fawad Ishfaq and Bushra KhanamMohammad Afaque Alam, Muhammad Fawad Ishfaq and Bushra Khanam
  
  Improvements in the care of patients with cardiovascular disease have led to improved survival but also a burgeoning population of patients with advanced heart disease. Cardiac stem cells (CSC) continue to promise opportunities to repair damaged cardiac tissue. However, precisely how stem cells accomplish cardiac repair, especially after ischemic damage, remains controversial. It has been postulated that the clinical benefit of adult stem cells for cardiovascular disease results from the release of cytokines and growth factors by the transplanted cells, stimulation of new blood vessel growth, enhancing tissue perfusion, and via preservation or even regeneration of myocardial tissue, leading to improvements in cardiac performance after myocardial infarction and in patients with advanced heart failure, reducing inflammation, and scar formation, as well as protecting cardiomyocytes from .. Read More»
  DOI: 10.4172/2168-9547.1000159

  Abstract PDF