Journal of Clinical Case Reports

Mohammed Ehlayel

Publications

• Case Report
  Autoimmune Encephalitis as the Sole Presentation of Common Varaible Immunodeficiency: First Report in a Child
  Author(s): Abdulhafeez M Khair, Mohammed Ehlayel, Rana Alshami and Khalid MohamedAbdulhafeez M Khair, Mohammed Ehlayel, Rana Alshami and Khalid Mohamed
  
  Background: Common Variable Immunodeficiency (CVID) is a clinically heterogeneous antibody deficiency syndrome. The usual presentation is with recurrent respiratory infections. There is a strong association between CVID and autoimmune disorders. However, for CVID to present initially and solely with Autoimmune Encephalitis (AIE) is extremely rare. Case report: A previously healthy three years old boy presented with acute encephalopathy and intractable seizures. His clinical features and radiological findings were highly suggestive of AIE. His evaluation has revealed findings consistent with diagnostic criteria of CVID. Recurrent infections have later on evolved during his prolonged illness. Discussion: Both CVID and AIE pose a diagnostic difficulty. The prevalence of autoimmune disorders in CVID patients’ cohort can be up to 50%. However, central nervous system involvement in th.. Read More»
  DOI: 10.4172/2165-7920.1000665

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