Journal of Cytology & Histology

Mona H Raafat

Publications

• Research Article
  Histological Study on Possible Therapeutic Effect of BM-MSCs on Healing of Lung Fibrosis Induced by CCl₄ with Reference to Macrophage Plasticity
  Author(s): Ghada Galal Hamam, Mona H Raafat and Hany KK MostafaGhada Galal Hamam, Mona H Raafat and Hany KK Mostafa
  
  Background: Lungs are susceptible to several types of toxins. Macrophages may play role in lung fibrosis. Mesenchymal stem cells (MSCs) have several valuable functions that make them a promising therapeutic option in the field of regenerative medicine. Objectives: Investigate possible therapeutic effects of bone marrow (BM)-MSCs on lung injury induced by carbon tetrachloride (CCl4) in adult rats with reference to role of macrophages plasticity. Material and methods: Forty-five adult male albino Wistar rats were divided into four groups. Group I (control). Group II (CCl4): rats received intraperitoneal injection of CCl4 (0.1 ml/100 g body weight) twice weekly for two weeks. Group III (BM-MSCs treated) received single injection of BM-MSCs after last injection of CCl4 .. Read More»
  

  Abstract PDF