Journal of Cytology & Histology

Mona H Raafat

Publications

• Research Article
  Effect of N-Acetyl Cysteine on Doxorubicin Induced Cardiotoxicity in Adult Male Albino Rat: Histological Study
  Author(s): Hany KK Mostafa and Mona H RaafatHany KK Mostafa and Mona H Raafat
  
  Introduction: Cardiotoxicity is one of the most important causes that limit the use of Doxorubicin (DOX) in treatment of the cancer. N-acetylcysteine (NAC) is an antioxidant substance that protects different cellular organelles from free radicals. The aim of the work: To shed the spot on the role of NAC on cardiotoxicity induced by DOX. Materials and methods: Forty adult male albino rats were divided into three groups. Group I: it was formed of 20 animals served as a control group. Further, it was divided into two subgroups; Subgroup Ia: formed of 10 animals received physiologic saline and Subgroup Ib: formed of 10 animals received NAC. Group II: formed of 10 animals that received DOX dissolved in normal saline. Group III: formed of 10 animals that received DOX similar togroup II and NAC similar to subgroup Ib. At the .. Read More»
  

  Abstract PDF