Journal of Cytology & Histology

Monique Decastel

Publications

• Research Article
  Inflammatory and Cell Adhesion Protein Markers in Colorectal Cancer in Patients Seen at the Teaching Hospital of Guadeloupe: Role of NF kappaB and P-Selectin
  Author(s): Monique Decastel, Anne-marie Andrea, Marc Lubeth, Jacqueline Deloumeaux and Juliette Smith-ravinMonique Decastel, Anne-marie Andrea, Marc Lubeth, Jacqueline Deloumeaux and Juliette Smith-ravin
  
  Background: Previous reports have been published describing the role of protein markers in the development and progression of colorectal cancers (CRC). In those investigations, Nuclear Factor kappaB (NFκB) and the Hypoxia Inducible Factor-1α (HIF-1α) have emerged as markers of clinical interest. The aim of this study was to evaluate their expression in patients who underwent surgery for CRC in the Guadeloupe Teaching Hospital (GlpeTH). Methods: Tumour tissues and the normal mucosa from 67 patients of GlpeTH were immunohistochemically evaluated using antibodies against HIF-1α and NFκBp65. Additionally; we examined the expression of Vascular Endothelial Growth factor (VEGF), Vascular Cell Adhesion Molecule-1 (VCAM-1) and P-selectin, which was regulated by HIF-1α and NFκBp65, respectively. .. Read More»
  DOI: 10.4172/2157-7099.1000276

  Abstract PDF