Division of Infectious Diseases, IRCCS,
Ospedale San Raffaele Milan, Italy via Stamira d’Ancona, 20 20127 Milan
Italy
Research Article
Clinical and Virologic Characteristics of HIV-1 Positive Patients with Delta Hepatitis
Author(s): Morsica G, Peano L, Bagaglio S, Poli A, Hasson H, Messina E and Uberti-Foppa CMorsica G, Peano L, Bagaglio S, Poli A, Hasson H, Messina E and Uberti-Foppa C
Background and Aim: Hepatitis Delta Virus (HDV) infection has been mainly studied in HIV negative patients, while data on HIV-1 positive patients are limited. We investigated the virological pattern as well as biochemical and clinical features of liver disease and immune status in HIV-1 positive patients with delta hepatitis. Their clinical characteristics were compared with those of anti-HDV negative, hepatitis B surface antigen (HBsAg) positive/HIV+ patients.
Methods: This retrospective study included HBsAg positive subjects with anti-HDV serology available, during the period 2010-2017. Biochemical and virological parameters were obtained at last visit in 2017 for each patient. Potential determinants for HDV positivity were examined by applying multivariate regression model.
Results: Of 78 HBsAg positive patients 19 (2.. Read More»
DOI:
10.4172/2155-6113.1000782
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report