Section of Histopathology, Aga Khan University Hospital,
Stadium Road, Karachi, 74800
Pakistan
Research Article
Role of CD10 Immunoshistochemical Expression in Discriminating the Categories of Phylloides Tumor
Author(s): Muhammad Usman Tariq, Saroona Haroon and Naila KayaniMuhammad Usman Tariq, Saroona Haroon and Naila Kayani
Background and objectives: Phylloides tumors are categorized as benign, borderline and malignant on the basis of histological features which are subjected to significant inter-observer variability. Our aim was to study the role of immunohistochemical expression of CD10 in discriminating benign, borderline and malignant categories of phylloides tumor.
Methods: The expression of CD10 was studied in 85 phylloides tumors (27 benign, 25 borderline, and 33 malignant) using immunohistochemistry to see whether the expression differed between these histologic categories. Chi-square test was applied to determine the significance of difference in CD10 expression among tumor categories. Significance was established at p<0.05.
Results: 5/27 (18.5%) benign, 16/25 (64%) borderline and 26/33 (78.8%) malignant cases expressed signif.. Read More»
DOI:
10.4172/2157-7099.1000292
Journal of Cytology & Histology received 2334 citations as per Google Scholar report