Journal of Oncology Translational Research

Munira A AlKhashan

Publications

• Research Article
  Platelet Transfusion Refractoriness among Patients with Hematological Malignancies in a Tertiary Center in Saudi Arabia
  Author(s): Khadega A Abuelgasim, Salwa R AlR ashed AlHumaid, Atheer S AlOtaibi, Munira A AlKhashan and Yosra Z AliKhadega A Abuelgasim, Salwa R AlR ashed AlHumaid, Atheer S AlOtaibi, Munira A AlKhashan and Yosra Z Ali
  
  Patients with hematological malignancies (HMs) and that undergoing hematopoietic stem cell transplantation (HSCT) for HMs or other disorders require multiple blood product transfusions. Approximately 30% of these patients develop platelet transfusion refractoriness (PTR), which increases the risk of serious and potentially fatal bleeding complications. The incidence of PTR in the Saudi population is unknown. To determine the occurrence of PTR in adult HMs and HSCT patients at King Abdul-Aziz Medical City (KAMC), Riyadh, we performed a study of 29 HMs and HSCT patients. Platelet counts were determined prior to and one hour after each platelet transfusion event. Four (13.8%) patients qualified for PTR, as they had corrected count increment of less than 5000 following two consecutive platelet transfusions. PTR was detected following 17 of the 102 (16.7%) platelet transfusion ev.. Read More»
  DOI: 10.4172/2476-2261.1000112

  Abstract PDF