Nuclear Medicine & Radiation Therapy

Mutahir Tunio

Publications

• Research Article
  Sequential Adjuvant Chemotherapy and Radiotherapy in Treatment of Early Stage Endometrial Carcinoma: Single Institutional Experience
  Author(s): Mutahir Tunio, Mushabbab Al Asiri, Abdul Rehman Alhadab, Yasser Bayoumi, Eyad Alsaeed, Khalid Riaz, Abdullah Amro, Abdel Salam Ismail and Abdel Aziz AlObaidMutahir Tunio, Mushabbab Al Asiri, Abdul Rehman Alhadab, Yasser Bayoumi, Eyad Alsaeed, Khalid Riaz, Abdullah Amro, Abdel Salam Ismail and Abdel Aziz AlObaid
  
  Background: Aim was to evaluate the additional benefit of adjuvant chemotherapy in patients of early stage endometrial carcinoma (EC) with adverse features. Materials and methods: Between June 2006 and July 2011, 56 patients with EC after surgery were randomized to receive either adjuvant radiotherapy (RT) [35 patients] or adjuvant sequential chemotherapy and radiotherapy (CRT) [21 patients]. Median age was 57.6 years (40-80). Predominant stages were FIGO IB (44.6%) and IIA (26.7%). Mean body mass index was 35.9 kg/m2 (23-72). Results: Median follow-up was 55 months (6-60). The Kaplan-Meier estimates for loco regional control (LRC), distant metastasis control (DMC) and overall survival (OS) for RT and CRT arms were; 85.7% vs. 74.2% (p 0.04), 85.7% vs. 85.7% (p 0.9) and 82.8% vs. 81% (p 0.8) respectively. Patients in CRT arm had earlier and higher pelvic recurrences {ha.. Read More»
  DOI: 10.4172/2155-9619.S6-010

  Abstract PDF