Egypt
Research Article
Effect of Anthum Graveolens L. Extract on Biochemical and Histopathological Alteration of Deltamethrin in Rats
Author(s): Somia I. El-Maghraby, Hamdy A. Taha and Nabila S. HassanSomia I. El-Maghraby, Hamdy A. Taha and Nabila S. Hassan
Anthum graveolens (dill) seeds are a common and very effective household remedy for a wide range of digestive problems. The present study was performed to investigate the effect of dill extracts on altered biochemical parameters in deltamethrin-exposed rats. Deltamethrin was adminis- tered orally at doses 7.5 and 15 mg /kg of body weight on the basis of LD 50 for 30 days. The sub-acute toxicity of pyrethroid insecticide deltamethrin varies markedly with the dose employed. Oral administration of plant extracts to rats for 30 days afforded a good protection against deltamethrin elevation in serum marker enzymes. They decreased the lev- els of aspartate aminotransferase (AST), alanine ami- notransferase (ALT) and alkaline phosphatase (ALP) which was increased by DLM administration. Deltamethrin sig- nificantly increased the level of plasma total.. Read More»
DOI:
10.4172/1948-593X.1000014
Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report