Nuclear Medicine & Radiation Therapy

Narayana Murthy P

Publications

• Research Article
  Hypofractionated IMRT Breast Treatment with Simultaneous Versus Sequential Boost Techniques
  Author(s): Suresh Moorthy, Elhateer H, Saroj Kumar Das Majumdar, Shubber Mohammed, Zainab Al Haddad and Narayana Murthy PSuresh Moorthy, Elhateer H, Saroj Kumar Das Majumdar, Shubber Mohammed, Zainab Al Haddad and Narayana Murthy P
  
  Purpose: Whole breast irradiation is part of breast conservative management for early breast cancer; addition of boost dose to tumor bed improves local recurrence rates and is currently the standard of care. Randomized trials reported low a/b ratio for breast cancer that predict a radiobiological advantage for hypofractionation. Simultaneous boost radiation as a method of hypofractionation proved safe and effective for head and neck tumors. In this study we attempt to compare and analyze the dosimetric aspects of adding Simultaneous Integrated Boost (SIB) over Sequential Boost (SB) to a hypofractionated treatment schedule in breast cancer patients after BCS. Materials and methods: CT simulation data sets for 23 patients were selected for this planning study; Targets and OAR were delineated as per RTOG guidelines. Multiple dynamic field IMRT plans were genera.. Read More»
  DOI: 10.4172/2155-9619.1000130

  Abstract PDF