Journal of Nephrology & Therapeutics

Narayana S. Murali

Publications

• Research Article
  Pilot Study of the Effect of Lanthanum Carbonate (Fosrenol®) In Patients with Calciphylaxis: A Wisconsin Network for Health Research (WiNHR) Study
  Author(s): Micah R Chan, Fadi Ghandour, Narayana S. Murali, MJ Washburn and Brad C. AstorMicah R Chan, Fadi Ghandour, Narayana S. Murali, MJ Washburn and Brad C. Astor
  
  Background: Currently there is a lack of effective treatment options for patients with calciphylaxis. There is anecdotal evidence that non-calcium based phosphorus binders may offer some benefit. The aim of this pilot study is to determine if lanthanum carbonate is effective in inducing remission of calciphylaxis lesions and demonstrate an improved DLQI (Dermatology Life Quality Index). Methods: This is a multi-site exploratory pilot study conducted through the Wisconsin Network for Health Research (WiNHR), a collaboration of health services researchers across the state of Wisconsin. Dialysis patients were recruited from in-center dialysis units, clinics and hospital admissions over a period of 24-months. Results: Due to the low inclusion rate, the trial was terminated after which 4 patients were prospectively analyzed. Dose of lanthanum carbonate was escalated to 3750 mg divided into.. Read More»
  DOI: 10.4172/2161-0959.1000162

  Abstract PDF