Egypt
Research Article
Histological, Immunohistochemical and Biochemical Study on the Possible
Cardioprotective and Antihypertensive Role of the Flavonoid in Unilateral Renal Artery Ligation of Adult Albino Rats
Author(s): Eman Mohamed Faruk, Naser A. ElSawy and Rania Ebrahim El desokyEman Mohamed Faruk, Naser A. ElSawy and Rania Ebrahim El desoky
The blood pressure lowering effect of herbal-rich diet is a necessary dietary lifestyle measure now included the guidelines for the management of arterial hypertension. Flavonoids represent a major class of plant polyphenolics, they have antioxidant effects and show a wide range of pharmacological activities. This study was to clarify the antihypertensive effect of the flavonoid extracted from the Origanum vulgare. Forty five adult male albino rats were classified into three main groups as follows: group I: control. Group II: hypertension was induced by ligation of left renal artery. Group III: hypertension was induced and given OV as 100 mg/kg body weight daily for eight weeks. Blood samples were collected and cardiac sections were stained with H&E and immunohistochemical staining for caspase 3 and Bcl-2. The body weight of control, hypertensive and treated hypertensive groups sh.. Read More»
DOI:
10.4172/2157-7099.1000326
Journal of Cytology & Histology received 2476 citations as per Google Scholar report