Journal of Cytology & Histology

Nashwa Fathy Gamal El-Tahawy

Publications

• Research Article
  Effect of Hydroxyprogesterone (17-OHPC) on Placenta in a Rat Model of Preeclampsia: Histological and Immunohistochemical Study
  Author(s): Nada Amgad Mohammed, Azza Hussein Ali, Nashwa Fathy Gamal El-Tahawy and Rehab Ahmed RifaaiNada Amgad Mohammed, Azza Hussein Ali, Nashwa Fathy Gamal El-Tahawy and Rehab Ahmed Rifaai
  
  Background: Preeclampsia (PE) is a leading cause of maternal and fetal morbidity and mortality. Patients with severe PE exhibit significantly lower serum progesterone concentrations. There is limited information about the use of progesterone to manage or treat PE.Aim of the work: To investigate the possible protective and/or therapeutic effects of 17-hydroxyprogesterone caproate (17-OHPC) therapy in a rat model of PE and the possibly involved mechanisms that monitored biochemically, histologically, and immunohistochemically.Methods: Twenty-four pregnant female albino rats were randomly divided into 4 groups (6 rats/each): The control group, preeclampsia group (PE-group), prophylactic group, and treated group. The mean arterial blood pressure (MAP) and 24-hour protein in urine were determined. Rats were sacrificed at day 22.. Read More»
  DOI: 10.4172/2157-7099.1000496

  Abstract PDF