Journal of AIDS & Clinical Research

Natella Rakhmanina

Publications

• Case Report
  Hemorrhagic Stroke in an Adolescent Female with HIV-Associated Thrombotic Thrombocytopenic Purpura
  Author(s): Natella Rakhmanina, Edward CC Wong, Jeremiah C Davis and Patricio E RayNatella Rakhmanina, Edward CC Wong, Jeremiah C Davis and Patricio E Ray
  
  HIV-1 infection can trigger acute episodes of Idiopathic Thrombocytoponic Purpura (ITP), and Thrombotic Thrombocytopenic Purpura (TTP), particularly in populations with advanced disease and poor adherence to antiretroviral therapy (ART). These diseases should be distinguished because they respond to different treatments. Previous studies done in adults with HIV-TTP have recommended the prompt initiation or re-initiation of ART in parallel with plasma exchange therapy to improve the clinical outcome of these patients. Here, we describe a case of HIVTTP resulting in an acute hemorrhagic stroke in a 16 year old female with perinatally acquired HIV infection and non-adherence to ART, who presented with severe thrombocytopenia, microangiopathic hemolytic anemia, and a past medical history of HIV-ITP. Both differential diagnosis and treatments for HIV-ITP and HIV-TTP were considered simulta.. Read More»
  DOI: 10.4172/2155-6113.1000311

  Abstract PDF