Tanzania
Case Report
Precursor B-Cell Lymphoblastic Primary Cardiac Lymphoma – Case Report and Review of Literature
Author(s): Jayadev Manikkam Umakanthan, Dipesh Uprety, Keerthi Banda, Navin Victor and Herbert AuerbachJayadev Manikkam Umakanthan, Dipesh Uprety, Keerthi Banda, Navin Victor and Herbert Auerbach
Primary cardiac lymphoma (PCL) is an extremely rare malignancy and an uncommon presentation of Non-Hodgkin’s Lymphoma. We report the first case of Precursor B-cell lymphoblastic PCL. A 44 year old Caucasian woman presented to our institution with one week history of worsening dyspnea, leg swelling and a weight gain of 12 pounds. Urgent echocardiography revealed pericardial effusion with tamponade physiology. Subsequent imaging showed a mass in the right atrio-ventricular groove. Pericardiocentesis was performed and cytopathology showed malignant appearing immature lymphocytes. Immunophenotypic analysis revealed 85% of the cells to be CD19 and CD10 positive. The cells were negative for CD20, surface light chains, CD3 and CD5 consistent with immature B-cells. Terminal deoxynucleotidyl Transferase (TDT) was strongly positive confirming Precursor B-cell Lymphoblastic Lymphoma. Clini.. Read More»
DOI:
10.4172/2165-7831.1000133
Journal of Blood & Lymph received 443 citations as per Google Scholar report