Isfahan University of Medical Sciences,
Isfahan
West Indies
Research Article
Co Expression of CD14/45 and CD3/19 Markers is Unique Signature for
Identification of Differentiated Chondrocytes from hADSC
Author(s): Nazem Ghasemi, Hashemi beni B, Zarei R, Valiani A and Esfandiari ENazem Ghasemi, Hashemi beni B, Zarei R, Valiani A and Esfandiari E
Background: Stem cell based therapy is a new paradigm for treatment of many abnormal conditions such as cartilage lesions. Although this method has many beneficial therapeutic effects, the serious adverse event of stem cell transplantation such as tumorigenic capacity is not deniable. Thus, other strategy such as differentiated cells transplantation instead of stem cells transplantation has been proposed. Overall, before cell transplantation, in vitro cell isolation in order to raise the purity of transplanted cells is necessary. So, the aim of this study is to identifying a unique CD “signature” that could be ascribed specifically to the chondrocyte before cell transplantation.
Methods: Human adipose derived stem cells (hADSC) were isolated from lipoaspirate samples and were subjected to osteogenic and chondrogenic differentiation in culture medium which supplement.. Read More»
DOI:
10.4172/2157-7099.1000403
Journal of Cytology & Histology received 2476 citations as per Google Scholar report