Journal of Pharmacognosy & Natural Products

Ngugi M Piero

Publications

• Research Article
  Anti-Pyretic Properties of Methanolic Bark Extracts of Terminalia brownii in Wistar Rats (Rattus norvegicus)
  Author(s): Jane W Mbiri, Sichangi Kasili, Wilton Mbinda, Patrick D Kisangau and Ngugi M PieroJane W Mbiri, Sichangi Kasili, Wilton Mbinda, Patrick D Kisangau and Ngugi M Piero
  
  The conventional drugs used to manage fever are usually not affordable, not easily available and have adverse side effects. Alternative therapeutic agents, like medicinal plant derivatives, should therefore be developed because they have been reported to be more affordable, more readily available and have lesser side effects. Terminalia brownii is traditionally used to manage fever but this ethno-medicinal claim lacks scientific validation. The present study therefore evaluated the anti-pyretic activity of T. brownii in Wistar rats. Fresh bark samples of T. brownii were collected from Kitui County, Kenya. This study used 30 adult male Wister rats that were 2-3 months old and weighing 140-180 g was used for the experiments. Steam-distilled turpentine was the pyrogen used to induce pyrexia and Aspirin was used as the reference drug. The extract reduced the ele.. Read More»
  DOI: 10.4172/2472-0992.1000121

  Abstract PDF