Journal of AIDS & Clinical Research

Nhlonzi GB

Publications

• Research Article
  Vulval Tuberculosis: The Histomorphological Spectrum in Patients with HIV Co-Infection and AIDS
  Author(s): Nhlonzi GB, Ramdial PK, Nargan K, Lumamba KD, Pillay B, Kuppusamy JB, Naidoo T and Steyn AJCNhlonzi GB, Ramdial PK, Nargan K, Lumamba KD, Pillay B, Kuppusamy JB, Naidoo T and Steyn AJC
  
  Objective: Vulval tuberculosis (TB) is reported rarely. The histomorphological spectrum and diagnostic mimicry thereof in patients with concomitant HIV infection/ AIDS is unreported to date. This study aimed to appraise the histopathologic spectrum of vulval TB in HIV co-infected patients and to identify histopathological diagnostic challenges, mimicry and pitfalls. Methods: Ten year retrospective study that reappraised the histomorphological features of vulval TB in HIV-infected patients. Results: The clinical descriptions of the biopsied lesions from 19 patients that form the study cohort encompassed nodules (9), ulcers (5), hypertrophy/edema (3) and abscesses (2). The main microscopic features included necrotizing and non-necrotizing granulomatous inflammation, ulceration with a zoned inflammatory response and chronic suppurative inflammation. The necrotizing component had the ty.. Read More»
  DOI: 10.4172/2155-6113.1000719

  Abstract PDF