State University of New York Upstate Medical University,
Syracuse, NY
Tanzania
Research Article
Utilization of Radioimmunotherapy (RIT) and Hematopoietic Stem Cell
Transplantation (HSCT) in B-cell Non-Hodgkin�¢����s Lymphoma (NHL): 10 Year
Experience of a Single Community Cancer Center
Author(s): Nibal Saad, Kleanthe Kolizeras, Susan M Szpunar and Ayad Al-KatibNibal Saad, Kleanthe Kolizeras, Susan M Szpunar and Ayad Al-Katib
After Yttrium (Y90) Ibritumomab tiuxetan (Zevalin) and Iodine (131I) tositumomab (Bexxar) were approved by the
FDA, the improved response of B-cell NHL to this novel RIT makes it a promising alternative to more aggressive
treatment like HSCT. In this study, we describe the experience of a single community-based cancer with RIT and
HSCT in patients with B-cell NHL in terms of response, survival and toxicity. Retrospectively, we reviewed 75
patients with B cell NHL who were treated with either RIT (N=50) or HSCT (N=25) between 2003 and 2013. Choice
of treatment modality, i.e. RIT vs. HSCT was based on discretion of treating Oncologist taking into consideration
patient’s age, performance status, comorbidity and preferences. RIT-treated patients were older. HSCT was more
likely to be used in aggressive lymphoma and as a consolidation of primary therap.. Read More»
DOI:
10.4172/2155-9619.1000331
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report