First Unit of Oncologic Surgery, Regional Cancer Institute,
700483, Iasi
Romania
Review Article
Role of Sentinel Lymph Node in Early Stage of Uterine Cervical Cancer
Author(s): Mihaela Mădălina Gavrilescu, Ana-Maria Todosi, Nicolae Ioanid and Viorel ScripcariuMihaela Mădălina Gavrilescu, Ana-Maria Todosi, Nicolae Ioanid and Viorel Scripcariu
Cervical cancer is currently the second most common form of neoplasia worldwide and third in the female population. Dissemination can occur directly (isthmus, parametrium, vagina, urinary bladder and/or rectum), through the lymphatic system (parametrium, internal iliac, external iliac, common iliac, obturator lymph nodes and rarely in the inferior gluteus, superior gluteus, superior rectum, sacrum, aortic lymph nodes) and through the circulatory system (lung, mediastinum, bones, liver). The risk of pelvic lymph nodes invasion in stage IB (FIGO) is 9-17%. The standard surgical treatment, for stages IA2-IIA, is radical hysterectomy with pelvic lymphadenectomy. The risk of intraoperative (vessel or nerve damage) or postoperative complications (lymphedema) is not negligible. The sentinel node concept refers to the first lymph node in which the cancerous lymphatic drainage takes place. Thi.. Read More»
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