Journal of Computer Science & Systems Biology

Nicolas Fontaine

Publications

• Research Article
  Modeling of a Cell-Free Synthetic System for Biohydrogen Production
  Author(s): Nicolas Fontaine, Brigitte Grondin-Perez, Frederic Cadet and Bernard OffmannNicolas Fontaine, Brigitte Grondin-Perez, Frederic Cadet and Bernard Offmann
  
  Hydrogen is a good candidate for the next generation fuel with a high energy density and an environment friendly behavior in the energy production phase. Micro-organism based biological production of hydrogen currently suffers low hydrogen production yields because the living cells must sustain different cellular activities other than the hydrogen production to survive. To circumvent this, teams have explored the synthetic assembly of enzymes in-vitro in cell-free systems with specific functions. Such a synthetic cell-free system was recently devised by combining 13 different enzymes to synthesize hydrogen from cellulose or cellobiose with better yield than microorganism-based systems. We used methods based on differential equations calculations to investigate how the initial conditions and the kinetic parameters of the enzymes influenced the productivity of a such system and, through.. Read More»
  DOI: 10.4172/jcsb.1000181

  Abstract PDF