Molecular Biomarkers & Diagnosis

Nikola Curic

Publications

• Research Article
  Biochemical Bone Markers as Predictors of Excessive Bone Turnover Suppression during Osteoporosis Treatment with Bisphosphonates
  Author(s): Branka Kovacev-Zavisic, Tijana Icin, Jovanka Novakovic-Paro, Milica Medic-Stojanoska, Milena Mitrovic, Dragana Tomic – Naglic, Ivana Bajkin, Nikola Curic, Milan Dolga and Nemanja KovacevBranka Kovacev-Zavisic, Tijana Icin, Jovanka Novakovic-Paro, Milica Medic-Stojanoska, Milena Mitrovic, Dragana Tomic – Naglic, Ivana Bajkin, Nikola Curic, Milan Dolga and Nemanja Kovacev
  
  Background: It should be decided before the introduction of osteoporosis therapy whether to start the therapy with the inhibitor of resorption or with the stimulator for bone formation. The decision should also be made during the therapy with antiresorptives regarding the appropriate time to stop the therapy and start the therapy with stimulators for bone formation. Assuming that normal or reduced levels of bone metabolism is limiting factor for initiation of antiresorptive therapy, and thereafter the appropriate parameter for the decision to stop antiresorptive therapy and start with stimulators of bone metabolism, we believe that the determination of bone markers should be compulsory and an integral part of the diagnostic procedure. The aim of this study was to determine whether antiresorptive therapy leads to satisfactory or excessive suppression of bone metabolic activity dependin.. Read More»
  DOI: 10.4172/2155-9929.S10-001

  Abstract PDF