Memorial Hospital, Biochemistry Laboratory,
İstanbul
Turkey
Research Article
Urinary NGAL in Prediction of Acute Kidney Injury
Author(s): Nilgün TekkeşinNilgün Tekkeşin
The incidence of acute kidney injury (AKI, previously referred to as acute renal failure) is reaching epidemic pro- portions. In this situation, early intervention can significantly improve the prognosis. Despite significant improvements in therapeutics, the mortality and morbidity associated with AKI remain high. A major reason for this is the lack of early markers for AKI, akin to troponins in acute myocardial disease, and hence an unacceptable delay in initiating therapy. Unfortunately, serum creatinine (SCr) is a delayed and unreliable indicator of AKI. The authors have previo - usly shown that urine neutrophil gelatinase-associated lipocalin (NGAL) is an early predictive biomarker of acute kid- ney injury (AKI) after cardiopulmonary bypass (CPB). In this study, the evidence for the role of NGAL measurements in AKI after CPB is explored. The emerging utility.. Read More»
DOI:
10.4172/2161-0959.1000111
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report