Transplantation Technologies & Research

Nobuhiko Satoh

Publications

• Review Article
  Acute Kidney Injury as a Risk Factor for Transplant Graft Failure
  Author(s): Motonobu Nakamura, Shoko Horita, Masashi Suzuki, Osamu Yamazaki, Nobuhiko Satoh and George SekiMotonobu Nakamura, Shoko Horita, Masashi Suzuki, Osamu Yamazaki, Nobuhiko Satoh and George Seki
  
  Acute kidney injury (AKI) has long-term biological effects on many organ systems and high mortality. Incomplete recovery of renal function from AKI is frequently observed, particularly when AKI is superimposed on chronic kidney disease (CKD), and this situation may further facilitate the progression of CKD. Patients with severe AKI in the intensive care unit typically have several failed extrarenal organ systems, including haemodynamic instability and respiratory failure. Consistent with these observations, AKI is associated with increased rates of graft failure and mortality after non-renal transplantation. For example, AKI is a common complication of liver transplantation and is associated with reduced patient and graft survival. AKI after lung transplantation also affects the clinical outcomes. The toxicity of calcineurin inhibitors, intraoperativ.. Read More»
  DOI: 10.4172/2161-0991.1000140

  Abstract PDF