Nuclear Medicine & Radiation Therapy

Nurdan Tacyildiz

Publications

• Case Report
  Assessment of Sorafenib and AntiVEGF Combination Therapy Response which Added to Neoadjuvant Therapy in two Pediatric Metastatic Ewing Sarcoma Patients by Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography (18F-PET) Method: It may Determine the Prognosis
  Author(s): Nurdan Tacyildiz, Gulsah Tanyildiz, Cigdem Soydal, Elgin Ozkan, Ozlem Kucuk, Gulsan Yavuz, Emel Unal, Handan Dincaslan, Yusuf Yildiz, Esra Pekpak, Zulfikar Gordu and Basak AksoyNurdan Tacyildiz, Gulsah Tanyildiz, Cigdem Soydal, Elgin Ozkan, Ozlem Kucuk, Gulsan Yavuz, Emel Unal, Handan Dincaslan, Yusuf Yildiz, Esra Pekpak, Zulfikar Gordu and Basak Aksoy
  
  Background: The prognosis is still poor in metastatic Ewing sarcoma (ES) patients. We aimed to assess importance of 18F-PET/CT in 2 pediatric local invasive/ metastatic Ewing sarcoma patients which have been performed antiVEGF and Sorafenib besides their neo-adjuvant and adjuvant chemotherapies (ChT) to improve their prognosis. Response to therapy has been followed by 18F-PET/CT in addition to MR imaging. Patients: First patient was a 12 year-old-girl who was suffering from right leg pain and diagnosed with Ewing sarcoma (ES). 18F-PET/CT showed a locally invasive mass with 14x5 cm dimensions located on one third of proximal tibia with a 5,1 SUVmax value was observed . After 4 cycles of conventional ChT beside antiVEGFSorafenib, SUVmax: 2,1 and tumor necrosis was 80%. Patient received local Radiotherapy (RT) and still in.. Read More»
  DOI: 10.4172/2155-9619.1000212

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