Tanzania
Research Article
Predictors of Mortality in a Clinic Cohort of HIV-1 Infected Children Initiated on Antiretroviral Therapy in Jos, Nigeria
Author(s): Augustine O Ebonyi, Augustine O Ebonyi, Seema T Meloni, Solomon A Sagay, Demetrios N Kyriacou, Chad J Achenbach, Oche O Agbaji, Tinuade A Oyebode, Prosper Okonkwo, John A Idoko and Phyllis J KankiAugustine O Ebonyi, Augustine O Ebonyi, Seema T Meloni, Solomon A Sagay, Demetrios N Kyriacou, Chad J Achenbach, Oche O Agbaji, Tinuade A Oyebode, Prosper Okonkwo, John A Idoko and Phyllis J Kanki
Background: Mortality among Human Immunodeficiency Virus-1 (HIV-1) infected children initiated on Antiretroviral Therapy (ART) though on a decline still remains high in resource-limited countries. Identifying baseline factors that predict mortality could allow their possible modification in order to improve pediatric HIV care and reduce mortality. Methods: We conducted a retrospective cohort study analyzing data on 691 children, aged 2 months-15 years, diagnosed with HIV-1 infection and initiated on ART between July 2005 and March 2013 at the pediatric HIV clinic of Jos University Teaching Hospital. Lost to follow-up children were excluded from the analyses. A multivariate Cox proportional hazards model was fitted to identify predictors of mortality. Results: Median follow-up time for the 691 children initiated on ART was 4.4 years (interquartile range (IQR), 1.8-5.9) and at the end o.. Read More»
DOI:
10.4172/2155-6113.1000403
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report