Federal Medical Center,
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Nigeria
Research Article
A Prospective Assessment of Autoimmune Sensitization of Hypertensive Patients on Antihypertensive Therapy: A Hospital Based Study
Author(s): Ogbonna Collins Nwabuko, Innocent Ijezie Chukwuonye and May Gogo NwabukoOgbonna Collins Nwabuko, Innocent Ijezie Chukwuonye and May Gogo Nwabuko
Background: Autoimmune sensitization by antihypertensive drugs is an emerging cause of morbidity and mortality among hypertensive on antihypertensive therapy and little is known about it in our environment. The aim of this study is to evaluate autoimmune sensitization among hypertensive patients on antihypertensive therapy using DAT (Direct Antiglobulin test or Direct Coomb’s test) and Hemoglobin concentration.Materials and method: This was a 4-month single center prospective study of 60 hypertensive patients on antihypertensive drugs and 40 age and sex matched control who were attending Cardiology Clinic in BMSH Port Harcourt. Hemoglobin concentration, Packed Cell Volume (PCV) and DAT were obtained using Cyanmethemoglobin, Microhematrocrit and Conventional tube methods respectively, while other clinical data were obtained using structured.. Read More»
DOI:
10.4172/2165-7831.1000183
Journal of Blood & Lymph received 443 citations as per Google Scholar report