Journal of Cytology & Histology

Oguzhan Karatepe

Publications

• Research Article
  The Comparison between Laparoscopic vs. Open Surgery for Trinitrobenzene Sulfonic Acid-Induced Rat Colitis
  Author(s): Oguzhan Karatepe, Suleyman Kokdas, Sedat Kamali, Timucin Aydın, Ahu Kemik, Gulcin Kamali, Gokhan Adas and Enis YuneyOguzhan Karatepe, Suleyman Kokdas, Sedat Kamali, Timucin Aydın, Ahu Kemik, Gulcin Kamali, Gokhan Adas and Enis Yuney
  
  Introduction: The etipathogenesis of inflammatory bowel disease (IBD) includes immunologic, genetic and environmental factors. In addition to the colon, frequent extra-intestinal alterations related to pancreas and hepatobiliary system are evaluated in several studies. A minimally invasive approach was applied to the IBD, with the expectation of earlier recovery, fewer postoperative complications. The aim of the study is to compare the effects of laparoscopic and open techniques applied for the surgical treatment of ulcerative colitis on the gastrointestinal system and pancreas, and related systemic consequences. Methods: Colitis was induced in 20 rats by rectal injection of a 5% 0.25mL 10mg/kg TNBS (Sigma, USA) in 50% ethanol. The rats were randomly divided into two groups: rat control, laparotomy was made for two-hour duration (n=10), a pneumoperitoneum was applied for a two-hour .. Read More»
  DOI: 10.4172/2157-7099.1000109

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