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Analysis of Total Urine Proteins: Towards a Non-Invasive Approach for Diagnosis of Visceral Leishmaniasis
Author(s): Om Prakash Singh and Shyam SundarOm Prakash Singh and Shyam Sundar
Diagnosis of Visceral Leishmaniasis (VL) is a major obstacle in the control of this disease, as demonstration of parasite by splenic or bone-marrow aspiration is almost impossible in the peripheral rural areas because of lack of facilities. In order to identify a non-invasive biomarker for VL, we employed two-dimensional electrophoresis (2D-PAGE) coupled with mass spectrometry through a comparison of urinary proteome. Though, we did not find the biomarker protein for VL, our findings provide some basic insights for future development of non invasive diagnostic tool... Read More»
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report