Journal of Clinical Case Reports

Ortega MP

Publications

• Case Report
  Coexisting B- Cell Lymphoma and Benign Mesenchymal Phospaturic Tumor: Debut as Acute Renal Failure Associated with Hypercalcemia and Hypophosphatemia
  Author(s): Navas-Parejo AMC, Ortega MP, Molina MC, Terán CMB and Soto JBNavas-Parejo AMC, Ortega MP, Molina MC, Terán CMB and Soto JB
  
  The present case starts as an acute renal failure related to severe hypercalcemia, hypophosphatemia, increased FGF-23 and decreased TRP. All the previous are associated with increased bone exchange rate, low PTH, undetectable levels of PTH-RP, 1-25 OH Vitamin D3 in upper level of normal range and bone densitometry compatible with osteoporosis in trabecular bone. These results seem compatible with an increase in bone resorption, urinary loss of calcium and phosphate, and none induced by PTH. Complementary studies suggest the spleen is the organ directly related with this case. In conclusion, a B Cell Lymphoma was diagnosed. It explained the causes of the hypercalcemia, either by the effect of a lymphotoxin, TNF or interleukin 1. After total remission of the lymphoma, the hypophosphatemia persisted, as did the Hight levels of FGF-23, low levels of TPR and a pathological bone densitometry. .. Read More»
  DOI: 10.4172/2165-7920.10001137

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