Switzerland
Research Article
Long-Term Post-Treatment MR and PET/CT Imaging in Prostate Cancer Patients in Complete Remission after Curative Radiotherapy with or without Androgen Deprivation: The Image of Cure
Author(s): Raymond Miralbell, Hansjörg Vees, Osman Ratib, Michael Wissmeyer, Charles Steiner, Yann Seimbille, Haleem G. Khan and Franz BucheggerRaymond Miralbell, Hansjörg Vees, Osman Ratib, Michael Wissmeyer, Charles Steiner, Yann Seimbille, Haleem G. Khan and Franz Buchegger
Purpose: To investigate the risk of false positive MRI and 18F-Fluorocholine (FCH) or 11Cacetate (AC) PET/ CT in prostate cancer patients with long term biochemical and clinical remission after curative radiation therapy (RT).
Methods and Materials: Twenty patients underwent MRI studies including T2-weighted, diffusion weighted, dynamic contrast-enhanced, and spectroscopic imaging. Nine of these patients were selected to have FCH and 10 AC PET/CT studies.
Results: MR spectroscopy suggested positive or equivocal results in 16/20 patients. However, the combined interpretation of all MRI sequences dropped the rate of suspicious or equivocal studies to 8/20. All but one patient underwent also PET/CT and early PET frames showed suspicious or equivocal local images in 15/19 patients (8/10 with AC, 7/9 with FCH). However, a com.. Read More»
DOI:
10.4172/2155-9619.1000118
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report