Journal of Health Education Research & Development

Pablo Gustavo Pieroni

Publications

• Research Article
  Novel Therapeutic Approach for Parkinson Disease during REM Sleep
  Author(s): Miguel Angel Pieroni and Pablo Gustavo PieroniMiguel Angel Pieroni and Pablo Gustavo Pieroni
  
  Study objectives: The physiological responses of an individual depend on preset limits. They must be able to adapt it to changing environmental conditions, modifying the thresholds. We propose a regulatory function of biological responses during REM sleep. Responses previously developed during wakefulness, are evaluated and regulated for integration into the repertoire of responses during sleep. The aims of this study were to evaluate the impact of the restoration of REM sleep in patients with Parkinson disease by stimulation of D2 receptors and to evaluate the symptomatic benefit of this approach. Methods: Ten parkinsonian patients underwent a polysomnography study using nocturnal apomorphine subcutaneous administration at the beginning of each REM detected along all night recording. Results: This therapeutic approach led to a significant benefit for patients in a.. Read More»
  DOI: 10.4172/2380-5439.1000164

  Abstract PDF