South Africa
Research Article
Increased Frequency of Guillain-Barré Syndrome in HIV Infection: A
Prospective Cohort Study
Author(s): Franclo Henning and Patrick BouicFranclo Henning and Patrick Bouic
Background: Guillain-Barré syndrome (GBS) has been reported in HIV-positive individuals, but the incidence and characteristics in this group of patients has not systematically been investigated beyond case reports and retrospective series. The aim of this study was to compare the incidence and characteristics of GBS in HIV positive and -negative individuals. Methods: We performed a prospective, comparative study over a 3 ½ year period in the Western Cape province of South Africa. All adult patients with GBS were included and classified into 2 groups based on HIV status. The two groups were compared with regards to clinical, electrophysiological and laboratory features. Patients were followed until stable or recovered, for a maximum of 12 months. Results: 28 patients were included in the study, of which 15 were HIV-positive. Using estimated HIV prevalence data for the sam.. Read More»
DOI:
10.4172/2155-6113.1000332
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report