Veterinary Science & Technology

Paul Gale

Publications

• Review Article
  Future Risk Assessments for the Impact of Climate Change on VectorBorne Viruses of Livestock: Potential of Genomics, Transcriptomics and Proteomics Approaches – A Review
  Author(s): Paul Gale, Ulrich RG and Wilson APaul Gale, Ulrich RG and Wilson A
  
  Climate and habitat change, together with globalisation, are important factors in the emergence of arthropodborne viruses (arboviruses). Changes in the range and abundance of the virus, vectors and hosts may create new combinations of host-pathogen-vector interactions for which data are not available. This paper reviews the genomics data currently available for arboviruses, their vectors and hosts, and assesses the level of understanding of the genetic factors affecting their adaptation to climate. It is anticipated here that genomics, transcriptomics and proteomics approaches may enable the breakdown of the traditional risk assessment pathways into the individual biochemical steps for each of the three interfaces between the virus, vector and host such that future risk assessments could be based on looking for certain gene combinations and their resulting expression profiles. Differe.. Read More»
  DOI: 10.4172/2157-7579.1000195

  Abstract PDF