Molecular and Genetic Medicine

Paul Sarnoski

Publications

• Research Article
  Comparison of A-type Proanthocyanidins in Cranberry and Peanut Skin Extracts Using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
  Author(s): Liyun Ye, Andrew Neilson, Paul Sarnoski, William Keith Ray, Susan Duncan, Renee Boyer and Sean Francis O’KeefeLiyun Ye, Andrew Neilson, Paul Sarnoski, William Keith Ray, Susan Duncan, Renee Boyer and Sean Francis O’Keefe
  
  Cranberry products have long been used to treat urinary tract infections. It is believed that the A-type proanthocyanidins in cranberries contribute to this function. Peanut is one of the other, few food sources that primarily contain A-type proanthocyanidins. The skin on the outside of the peanut kernels (testa), which is treated as an agriculture waste product, contains high levels of A-type proanthocyanidins. In this study, an HPLC diol column separation method and MALDI-TOF MS were used to characterize and compare the proanthocyanidin compositions of peanut skins and cranberries. MALDI-TOF MS in linear mode was able to detect a group of proanthocyanidins with DP (degree of polymerization) 10 in peanut skin extract, but was only able to detect DP 8 in cranberry extract. The reflectron mode showed clusters of clear narrow peaks at DP 7 in peanut skin extract, while the highest DP re.. Read More»
  

  Abstract PDF