Journal of AIDS & Clinical Research

Paula Frew

Publications

• Research Article
  Assessment of a Microbicide Candidate among a Diverse Cohort of Urban Southern US Women and their Male Sexual Partners
  Author(s): Paula Frew, Kimberly Parker, Takeia Horton, Brooke Hixson, Lisa Flowers, Frances Priddy, Lisa Grohskopf, Christine Mauck and Kimberly WorkowskiPaula Frew, Kimberly Parker, Takeia Horton, Brooke Hixson, Lisa Flowers, Frances Priddy, Lisa Grohskopf, Christine Mauck and Kimberly Workowski
  
  Background: This mixed methods study reports on product acceptance from a Phase I clinical trial of a candidate non-nucleoside reverse transcriptase inhibitor (NNRTI) vaginal microbicide product (UC781). The product was evaluated in the context of a Phase I clinical trial in an area characterized by high HIV prevalence among minority women. The findings will inform the development of an acceptable microbicide that will address the needs of diverse women and their partners. Methods: This is a mixed methods study of 34 racially and ethnically diverse female participants and 10 male partners in Atlanta, Georgia. Chi-square tests for marginal homogeneity and kappa statistics were calculated to analyze differences between groups on product attributes and use intention. ANOVA was used to examine difference between the treatment groups. Qualitative data were analyzed via constant comparative.. Read More»
  DOI: 10.4172/2155-6113.S4-004

  Abstract PDF